Prof. Dr. Sebahat Yılmaz Ağladıoğlu

Pediatric Endocrinology

Prof. Dr. Sebahat Yılmaz Ağladıoğlu

Obesity
Insulin resistance
Diabetes
Hypoglycemia (low sugar)
Growth retardation and short stature
Anorexia
growth hormone deficiency
Puberty problems (early puberty, delayed puberty, excessive hair growth, menstrual irregularity, polycystic ovary syndrome)
Turner syndrome
Thyroid diseases (Goiter, hypothyroidism, hyperthyroidism, Hashimoto's disease, thyroid nodule)
Sexual development disorders (small penis, undescended testis, gender ambiguity, hypospadias)
Adrenal gland diseases (Congenital adrenal hyperplasia, Addison's disease, Cushing's syndrome)
Bone and calcium metabolism diseases (rickets, vitamin D deficiency, osteoporosis)

Education:

University
• Ankara University Faculty of Medicine, Ankara 2002

Specialization training
• Gazi University Faculty of Medicine, Department of Child Health and Diseases, Ankara 2009

Subspecialty training
• Dr. Sami Ulus Maternity, Gynecology, Pediatric Health, and Diseases Training and Research Hospital, Ankara 2013

Academic Appointments:

Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital Pediatric Hematology 2008-2009
Dr. Sami Ulus Maternity, Child Health and Diseases Training and Research Hospital Pediatric Endocrinology 2009-2013
Pamukkale University Faculty of Medicine Department of Child Health and Diseases 2013 - 2016
London Great Ormond Street Hospital For Children ESPE Clinical Fellow 2014
Associate Professor 2016
Ersoy Private Hospital June 2017
Memorial Health Group August 2018

1. Bakkaloğlu SA, Söylemezoğlu O, Buyan N, Funahashi T, Elhan AH, Peru H, Fidan K, Yılmaz S, Hasanoğlu E. High serum adiponectin levels during steroid-responsive nephrotic syndrome relapse. Pediatr Nephrol. 2005 Apr;20(4):474-7.

2. Ağladıoğlu S, Beyazova U, Camurdan AD, Şahin F, Atak A. Immunogenicity ofrecombinant hepatitis B vaccine: comparison of two different vaccination schedules.Infection. 2010 Aug;38(4):269-73.

3. Öztürkmen S, Akyay A, Bıçakçı Z, Karakoç Y, Arıkan SM, Celebi-Tayfur A,AğladıoğluS, Olcay L. Delayed diagnosis of acute leukemia in a patient with bone pain and fracture. Turk J Pediatr. 2010 Sep-Oct;52(5):552- 5.

4. Aycan Z, Ağladıoğlu SY, Ceylaner S, Çetinkaya S, Baş VN, Peltek Kendirici HN. Sporadic Nonautoimmune Neonatal Hyperthyroidism Due to A623V Germline Mutation in the Thyrotropin Receptor Gene. J Clin Res Pediatr Endocrinol. 2010 Dec;2(4):168-72.

5. Çetinkaya S, Peltek Kendirici HN, Yılmaz Ağladıoğlu S, Baş VN, Özdemir S, Bozkurt C, Aycan Z. Hypothyroidism due to hepatic hemangioendothelioma: a case report. J Clin Res Pediatr Endocrinol. 2010 Sep;2(3):126-30.

6. Baş VN, Çetinkaya S, Yılmaz Ağladıoğlu S, Peltek Kendirici HN, Bilgili H, Yıldırım N, Aycan Z. Insulin oedema in newly diagnosed type 1 diabetes mellitus. J Clin Res Pediatr Endocrinol. 2010 Mar;2(1):46-8.

7. Polat S, Çamurdan AD, Aksakal N, Ağladıoğlu S, Beyazova U, Sahin F, Atak A, Er A. Evaluation of perinatal and intrafamilial hepatitis B prevention programmes in a well child clinic: 9-year follow-up study in Turkey. Trans R Soc Trop Med Hyg. 2011 Apr;105(4):220-5.

8. Aycan Z, Baş VN, Çetinkaya S, Ağladıoğlu SY, Kendirci HN, Senocak F. Thiamine- responsive megaloblastic anemia syndrome with atrial standstill: a case report. J Pediatr Hematol Oncol. 2011 Mar;33(2):144-7.

9. Yılmaz S, Tavil B, Sarı S, Cinaz P. Vitamin k deficiency because of ceftriaxone usage and prolonged diarrhoea. J Paediatr Child Health. 2011 May;47(5):314-5.

10. Ağladıoğlu SY, Beyazova U, Camurdan AD, Sahin F, Atak A. Immunogenicity of two different hepatitis B vaccine schedules. Infection. 2011 Jun 30.

11. Bıçakçı Z, Akyay A, Öztürkmen S, Çelebi-Tayfur A, Ağladıoğlu S, Ciledağ N, Ozçay F, Arda K, Olcay L. Conus medullaris syndrome and acute colonic pseudoobstruction in a child with acute lymphoblastic leukemia. Turk J Pediatr. 2011 Sep Oct;53(5):579- 82.

12. Ağladıoğlu SY, Aycan Z, Kendirci HN, Erkek N, Baş VN. Does pseudohypoaldosteronism mask the diagnosis of congenital adrenal hyperplasia? J Clin Res Pediatr Endocrinol. 2011;3(4):219-21.

13. Derinöz O, Belen F. B, Yılmaz S. Is tracheostomy suitable for securing airway after facial ?rearm injuries? World J Emerg Med, 2011 (2); 4:307-309.

14. Yılmaz Ağladıoğlu S, Aycan Z, Bas VN, Peltek Kendirci HN, Önder A. Thiamine- responsive megaloblastic anemia syndrome: a novel mutation. Genet Couns.2012;23(2):149-56.

15. Önder A, Kendirci HN, Bas VN, Ağladıoğlu SY, Çetinkaya S, Aycan Z. A pediatric Conn syndrome case. J Pediatr Endocrinol Metab. 2012;25(1-2):203- 6.

16. Aycan Z, Önder A, Çetinkaya S, Bilgili H, Yıldırım N, Baş VN, Peltek Kendirci HN, Ağladıoğlu SY. Assessment of the knowledge of diabetes mellitus among school teachers within the scope of the managing diabetes at school program. J Clin Res Pediatr Endocrinol. 2012 Dec;4(4):199-203.

17. Kendirci HN, Aycan Z, Çetinkaya S, Baş VN, Ağladıoğlu SY, Önder A. A rare combination: congenital adrenal hyperplasia due to 21 hydroxylase deficiency and turner syndrome. J Clin Res Pediatr Endocrinol. 2012 Dec;4(4):213-5.

18. Önder A, Aycan Z, Çetinkaya S, Kendirci HN, Bas VN, Ağladıoğlu SY. Assessment of the 21-hydroxylase deficiency and the adrenal functions in young females with Turner syndrome. J Pediatr Endocrinol Metab. 2012;25(7-8):681- 5.

19. Baş VN, Cangul H, Ağladıoğlu SY, Kendall M, Çetinkaya S, Maher ER, Aycan Z. Mild and severe congenital primary hypothyroidism in two patients by thyrotropin receptor (TSHR) gene mutation. J Pediatr Endocrinol Metab. 2012;25(11-12):1153- 6.

20. Aycan Z, Bas VN, Çetinkaya S, Yılmaz Ağladıoğlu S, Tiryaki T. Prevalence and long-term follow-up outcomes of testicular adrenal rest tumours in children and adolescent males with congenital adrenal hyperplasia. Clin Endocrinol (Oxf). 2013 May;78(5):667-72.

21. Ekşioğlu AS, Yılmaz S, Çetinkaya S, Cinar G, Yildiz YT, Aycan Z. Value of pelvic sonography in the diagnosis of various forms of precocious puberty in girls. J Clin Ultrasound. 2013 Feb;41(2):84-93.

22. Baş VN, Çetinkaya S, Ağladıoğlu SY, Aksoy A, Gülpınar B, Aycan Z. Report of the first case of precocious puberty in Rett syndrome. J Pediatr Endocrinol Metab. 2013 Apr 2:1-3.

23. Akyürek N, Aycan Z, Çetinkaya S, Akyürek O, Yılmaz AğladıoğluS, Ertan U. Peroxisome proliferator activated receptor (PPAR)-gamma concentrations in childhood obesity. Scand J Clin Lab Invest. 2013 Apr 23. [Epub ahead of print]

24. Baş VN, Aycan Z, Ağladıoğlu SY, Kendirci HN. Prevalence of hyperthyrotropinemia in obese children before and after weight loss. Eat Weight Disord. 2013 Mar;18(1):87- 90.

25. Ağladıoğlu SY, Cetınkaya S, Erdeve SS, Önder A, Kendırcı HN, Bas VN, Aycan Z. Diabetes mellitus with Laron syndrome: case report. J Pediatr Endocrinol Metab. 2013 May 17:1-4.

26. Yılmaz-Ağladıoğlu S, Savas-Erdeve S, Boduroğlu E, Önder A, Karaman I, Cetınkaya S, Aycan Z. A Girl with Steroid Cell Ovarian Tumor Misdiagnosed As Non-classical Congenital Adrenal Hyperplasia. Turk J Pediatr. 2013 Jul-Aug;55(4):443- 6.

27. Yılmaz Ağladıoğlu S, Savas Erdeve S, Çetinkaya S, Bas V.N, Peltek Kendirci H.N, Önder A, Aycan Z. Hyperinsulinemic Hypoglycemia: Experience With 17 Cases. J Clin Res Pediatr Endocrinol 2013 Sep 10;5(3):150-5

28. Baş VN, Ağladioglu SY, Önder A, Özışık P, Peltek Kendirci HN, Çetinkaya S, Aycan Z. Long-term follow-up of Cushing's disease:a case report. J Clin Res Pediatr Endocrinol. 2013 Sep 10;5(3):202-5.

29. Baş VN, Aycan Z, Cangül H, Kendall M, Ağladıoğlu SY, Çetinkaya S, Maher ER. A common thyroid peroxidase gene mutation (G319R) in Turkish patients with congenital hypothyroidism could be due to a founder effect. J Pediatr Endocrinol Metab. 2013 Oct 25:1-5.

30. Bayram O, Sebahat AY, Kadir A, Ali K. A rare cause of short stature: transsphenoidal encephalocele. Eur J Pediatr. 2013 Oct 19.

31. Önder A, Aycan Z, Koca C, Ergin M, Çetinkaya S, Ağladıoğlu SY, Peltek Kendirci HN, Baş VN. Evaluation of Asymmetric Dimethylarginine (ADMA) Levels in Children with Growth Hormone Deficiency. J Clin Res Pediatr Endocrinol. 2014 Mar 5;6(1):22-7. doi: 10.4274/Jcrpe.1182.

32. Nalcacioglu-Yuksekkaya P, Sen E, Yılmaz S, Elgin U, Gunaydin S, Aycan Z. Decreased retinal nerve fiber layer thickness in patients with congenital isolated growth hormone deficiency. Eur J Ophthalmol. 2014 May 1:0. doi:10.5301/ejo.5000481. [Epub ahead of print] PubMed PMID: 24803154.

33. Nalcacıoğlu-Yüksekkaya P, Sen E, Elgin U, Hocaoğlu M, Öztürk F, Yılmaz SA, Kendirci HN, Çetinkaya S, Aycan Z. Corneal properties in children with congenital isolated growth hormone deficiency. Int J Ophthalmol. 2014 Apr 18;7(2):317-20. doi:10.3980/j.issn.2222-3959.2014.02.22.

34. Savas-Erdeve S, Yılmaz Ağladıoğlu S, Önder A, Peltek Kendirci HN, Bas VN, Sagsak E, Çetinkaya S, Aycan Z. An Uncommon Cause of Hypoglycemia: Insulin Autoimmune Syndrome. Horm Res Paediatr. 2014 Jul 23.

35. Sagsak E, Önder A, Ocal FD, Tascı Y, Ağladıoğlu SY, et al. (2014) Primary Amenorrhea Secondary to Mullerian Anomaly. J Clin Case Rep S1: 007. doi:10.4172/2165-7920.S1- 007.

36. Yılmaz Ağladıoğlu S, Sagsak E, Aycan Z. Urinary C-Peptide/Creatinine Ratio Can Distinguish Maturity-Onset Diabetes of the Young from Type 1 Diabetes in Children and Adolescents: A Single-Center Experience. Horm Res Paediatr, 2015;84(1):54-61.

37. Baş VN, Yılmaz Ağladıoğlu S, Özgür S, Karademir S, Aycan Z. Investigation ofautoimmune diseases accompanying Hashimoto's thyroiditis in children andadolescents and evaluation of cardiac signs. J Pediatr Endocrinol Metab. 2015Jul;28(7-8):767- 71.

38. Kendirci HN, Ağladıoğlu SY, Önder A, Baş VN, Çetinkaya S, Aycan Z. Effects of GnRH analogue treatment on anterior pituitary hormones in children with centralprecocious puberty. J Pediatr Endocrinol Metab. 2015 Sep;28(9-10):1145- 51.

39. Ağladıoğlu K, Herek D, Herek O, Ağladıoğlu SY, Cördük N, Ozhan B. Canultrasound elastography be used as a new technique in the differentiation ofundescended testes and reactive lymph nodes in children? Clin Radiol. 2015 Nov;70(11):1269-75.

40. Özhan B, Yılmaz Ağladıoğlu S, Yüksel S, Sanlı B. Perioral Acanthosisnigricans. J Pediatr. 2015 Dec;167(6):1453. doi: 10.1016/j.jpeds.2015.08.046.

41. Guran T, Buonocore F, Saka N, Ozbek MN, Aycan Z, Bereket A, Bas F, Darcan S, Bideci A, Güven A, Demir K, Akıncı A, Büyükkınan M, Aydın BK, Turan S, Ağladıoğlu SY, Atay Z, Abalı ZY, Tarım O, Catli G, Yüksel B, Akcay T, Yıldız M, Özen S, Doger E, Demirbilek H, Ucar A, Isik E, Özhan B, Bolu S, Özgen IT, Suntharalingham JP, Achermann JC. Rare Causes of Primary Adrenal Insufficiency: Genetic andClinical Characterization of a Large Nationwide Cohort. J Clin Endocrinol Metab. 2016 Jan;101(1):284-92.

42. Kendirci HN, Ağladıoğlu SY, Baş VN, Önder A, Çetinkaya S, Aycan Z. Evaluating the Efficacy of Treatment with a GnRH Analogue in Patients with CentralPrecocious Puberty. Int J Endocrinol. 2015;2015:247386.

43. Ağladıoğlu SY, Aycan Z, Çetinkaya S, Baş VN, Önder A, Peltek Kendirci HN, Doğan H, Ceylaner S. Maturity onset diabetes of youth (MODY) in Turkish children:sequence analysis of 11 causative genes by next generation sequencing. J Pediatr Endocrinol Metab. 2016 Apr;29(4):487-96.

44. Işık-Balcı Y, Ağladıoğlu S, Ağladıoğlu K, Kılıç-Toprak E, Kılıç-Erkek O, Özhan B, Polat A, Bor-Küçükatay M. Impaired Hemorheological Parameters and IncreasedCarotid Intima-Media Thickness in Children with Subclinical Hypothyroidism. Horm Res Paediatr. 2016;85(4):250-6.

45. Acer S, Ağladıoğlu SY, Pekel G, Özhan B, Çetin EN, Yağcı R, Yıldırım C.Density of the crystalline lens in obese and nonobese children. J AAPOS. 2016Feb;20(1):54-7.

46. Acer S, Pekel G, Çetin EN, Yağcı R, Yıldırım C, Ağladıoğlu SY, Özhan B. Reply.J AAPOS. 2016 Aug;20(4):379-80.

47. Özdemir ÖM, Çıralı C, Yılmaz Ağladıoğlu S, Evrengül H, Tepeli E, Ergin H. Neonatal Bartter syndrome with cholelithiasis and hydrocephalus: Rareassociation. Pediatr Int. 2016 Sep;58(9):912-5.

48. Özhan B, Evrengul H, Yılmaz Ağladıoğlu S, Demir S. Vitamin D Status of Children in a University Hospital in West Turkey. HK J Paediatr (New Series) 2016;21:251-25

Pediatric Endocrinology